INTRODUCTION:

An Ayurvedic medication called Gaucho (Tinospora cord folia [Wild.] Mires.) is utilized in Rasayana Chikitsa.¹ Rejuvenation therapy, or rasayan, is one of the most important subfields in Ayurveda.² It is also referred to as Gurcha in Hindi, Amruthu in Malayalam, Amrutha balli in Kannada, Guduchi in Marathi and Sanskrit, etc. Anti-inflammatory, anti-diabetic, anti-arthritic, antioxidant, anti-stress, antileprotic, antimalarial, hepatoprotective, antiallergic, and immunomodulatory effects are only a few of its many therapeutic qualities.³ Medicinal plants have been known to exist since the prehistoric era, and they are employed in conventional medical procedures.

Plant-derived chemicals are effective against bacteria, fungi, insects, and illnesses. Medicinal plants are commonly employed in non-industrialized countries because they are easily accessible, safe, and less expensive than modern medication. Of the 3,00,000 plant species that are recognized globally, only 5% have undergone scientific investigation for their therapeutic intent.⁴ This herb's extract inhibits kidney hypertrophy and polyuria both lessen kidney damage. Guduchi's aqueous extract has antidyslipidemic properties, while its alcoholic extract has antihyperglycemic properties.⁵Guduchi is mentioned in Ayurvedic literature as an ingredient in a number of chemical formulations that are used to treat urinary tract infections, fever, dyspepsia, and general debility. The stem has a bitter stomachic effect, induces bile secretion, induces constipation, is a tonic, relieves fever, burning sensation, and thirst, prevents vomiting, is a diuretic, enriches the blood, treats jaundice, and is beneficial for skin conditions. The juice, on the other hand, is beneficial for diabetes, urethral and vaginal discharges, low fevers, and enlarged spleen, according to Ayurveda. As an antidote to scorpion stings and snake bites, the root and stem are recommended in combination with other medications. As a substitute and tonic, an infusion made from powdered stem has gained the reputation of being an aphrodisiac among ancient Hindu literature.

BOTANICAL DISCRIPTION

Fig 1: Cross section of stem of guduchi

SCIENTIFIC CLASSIFICATION:

Kingdom: plantea

Clade : Tracheophytes

Clade : Angiosperms

Clade : Eudicots

Order : Ranunculales

Family : Menispermaceae

Genus : T. cordifolia

MEDICINAL PROPERTIES OF GUDUCI:

Guduci is bestowed with the following healing properties.

Immunomudulator

Rejuvenative

Adaptogen

Anti-inflammatory

Mild Analgesic

Antioxident

Anticancer

Anti-stress

Antacid

Febrifuge

Anti-gout

According to Ayurveda one of the three Amrit plants is guduchi; the other two are haritaki and garlic. Liver damage could be caused by giloy juice.⁶
Ayurvedic medicines containing Guduchi number about 2400. These formulations, which come in over 24 dosage forms, such as Kwatha (~Decoction), Hima (~Cold infusion), Churna (~Powder), Swarasa (~Juice), Kalka (~Paste), Gutika (~Tablet/Pill), Ghrita (~Medicated Ghee), Avaleha (~Semisolid medicated confection), Taila (~Medicinal oil), Guggulu (~Medicinal Resin), Asava (~Fermented infusion), Arishta (~Fermented decoction), Arka (~Liquid preparation obtained by distillation), Bhasma (~Ashes of metals), Kshara (~Alkalies), Satva (~Essence), Vataka (~Pill), Kshirapaka (~Medicated milk), Sneha (~Lubricant), Takra (~Buttermilk), Yusha (~Soup), and jala (~Water) are indicated for treatment of approximately 95 clinical conditions. Guduchi is an approved ingredient in around 141 topical preparations in 14 different dosage forms. in 65 medical disorders.⁷Its broad applicability in a variety of therapeutic settings, dosage forms, and delivery methods (oral, topical, nasal, per-rectal, etc.) supports one of its synonyms, Bhishagpriya (~favored by physicians) (Annexure 1), in 65 different illness conditions. One of its synonyms, Bhishagpriya (preferred by doctors), is justified by its adaptable use in a variety of clinical circumstances, dose forms, and administration routes (oral, topical, nasal, per-rectal, etc.) (Annexure 1) Indigenous cultures in tropical and subtropical regions of Asia, Africa, and Australia also use this herb as a traditional medicine.⁸

Fig 2: Juice of guduchi

Nutritional Value of Guduchi:

The stem and the leaves of Guduchi have different nutritional values.

Table 1: Nutrients present in 100 grams of Guduchi leaves⁹

Nutrients	Fresh leaves	Dehydrated leaves
Carbohydrate (g)	3.34	7.53
Protein (g)	2.30	5.23
Fat (g)	0.36	1.05
Fibre (g)	11.321	52.295
Iron (mg)	5.87	22.55
Calcium (mg)	85.247	210
Vitamin C (mg)	56	16
Beta-carotene ( µg)	303.7	428.5
Energy (kcal)	88.64	240
Polyphenols (mg)	4.8	12.2
Flavonoids (mg)	6.76	18.28

BENEFITS OF GUDUCI:

Guduchi, or Tinospora cordifolia, is a plant whose health-promoting properties are so extensive that the plant has long been equated with the life-giving nectar of the gods. The word "Amrita," which means longevity, appears in the early Ayurvedic scriptures, indicating how highly esteemed this herb is as a necessary component of the Ayurvedic pharmacopeia. ¹⁰

Guduchi is known to support the body in the following ways:

· Boost immune function: Guduchi is an adaptogenic herb, meaning it can adjust to the body's needs and reduce the negative effects of stress while also boosting immunity and enhancing general health.

· Promotes Joint Comfort: Guduchi improves joint comfort and range of motion by strengthening joint tissue and removing built-up toxins from the joints.

GUDUCHI USES:

· Guduchi powder can be used with ginger to assist relieve joint pain.

· To improve vision, you can use boiled Guduchi powder mixed with water, let it cool, and then apply the resulting liquid to your eyelids.

· You are able to raise Ginger and guduchi powder can be used to relieve joint discomfort.

· You may boost the nutritional content by including the powdered and dried Guduchi leaves.

· Guduchi powder is a treatment for arthritis.

· Those who experience lightheadedness, liver problems, skin conditions, etc., can use it in combination with sugar candies.

· It can be used in conjunction with sugar candy for people who suffer from skin conditions, liver problems, vertigo, etc.

· It can be used in conjunction with sugar candy for people who suffer from skin conditions, liver problems, vertigo, etc.^11,12

Fig 3: Amruta

CONCLUSION:

Guduchi is a living example of the great wisdom of traditional medicine, with its many uses and prospective applications. Millions of people throughout the world continue to find hope and healing from this ancient plant, which has been shown to improve immunity, support liver health, and ease respiratory illnesses. As with any herbal therapy, it is best to see a licensed healthcare professional to fully utilize Guduchi while guaranteeing safe and efficient use.

REFERANCE:

1. Acharya VY, editor. Charaka Samhita of Agnivesha, Sutra Sthana, Ch.4, Ver. 18, 5th ed. Varanasi: Choukhamba Orientalia, 2001; 34.

2. Acharya VY, editor. Sushruta Samhita of Sushruta, Sutra Sthana, Ch. 1, Ver. 7, 7th ed. Varanasi: Choukhamba Orientalia, 2002; 3.

3. Mishra A, Kumar S, Pandey AK. Scientific validation of the medicinal efficacy of Tinospora cordifolia. Scientific World Journal, 2013; 2013: 292934.

4. Estari M, Venkanna L, Reddy AS (2012) In vitro anti-HIV activity of crude extracts from tinospora cordifolia. BMC Infect Dis 12: P10

5. 1. Anonymous. (1989). The Wealth of India, Raw materials. Vol-X, Revised

6. Kirtikar KR, Basu BD. Indian Medicinal Plants, Vol-I, 2005, International Book Distributors, India, pp 76-80.

7. Joy A, Mansukhbhai BM, Sojeetra NH, Acharya RN. Guduchi (Tinospora cordifolia (Wild.) Miers) and its therapeutic external applications: A comprehensive review. Indian J Ayu Integ Med 2021; 2: 56-63

8. Sensen Chi, Gaimei She, Dan Han, Weihua Wang, Zhao Liu, Bin Liu, “Genus Tinospora: Ethnopharmacology, Phytochemistry, and Pharmacology”, Evidence-Based Complementary and Alternative Medicine, vol. 2016, Article ID 9232593, 32 pages, 2016. https:// doi.org/10.1155/2016/9232593

9. Pandey M, Paul V, Singh P, Ali Z. Evaluation of nutritional composition and antioxidant activity of herbal leaves. World J Pharm Pharm Sci [Internet]. 2016 Jun 14 [cited 2022 May 25];5(8):1396-402. Available from: https://www.researchgate.net/profile/virginia-paul/publication/354461935_evaluation_of_nutritional_composition_and_antioxidant_activity_of_herbal_leaves/links/61399d99b1dad16ff9f065a0/evaluation-of-nutritional-composition-and-antioxidant-activity-of-herbal-leaves.pdf

10. Pole, Sebastian. Ayurvedic Herbs: The Principles of Traditional Practice. Churchill Livingstone, 2013. (189-190)

11. Parmar, Riddhi. “10 Health Benefits Of Giloy - the Ultimate Immunity Booster.” PharmEasy Blog, August 16, 2021. https://pharmeasy.in/blog/health-benefits-of-giloy-the-ultimate-immunity-booster

12. KD, Sannegowda KM; Venkatesha SH. Moudgil. “Tinospora Cordifolia Inhibits.” International Journal of Immunopathology and Pharmacology. U.S. National Library of Medicine. 10.1177/0394632015608248

Received on 21.06.2025 Revised on 16.08.2025

Accepted on 26.09.2025 Published on 22.01.2026

Available online from January 29, 2026

Asian J. Pharm. Res. 2026; 16(1):87-89.

DOI: 10.52711/2231-5691.2026.00011

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